Gain an expansive view of your solid tumor samples by targeting 523 cancer-related genes using the TruSight Oncology 500 assay. Not only does this assay identify all relevant variants (SNVs, insertions, deletions, CNVs, gene fusions, and transcript variants) across various tumor types, but it also reports tumor mutational burden (TMB) and microsatellite instability (MSI) scores.
Our comprehensive genomic panel has advantages over individual biomarker assays in its ability to detect multiple biomarkers with one test, saving time, money, and samples. Q2 Solutions can meet your profiling needs by leveraging trusted technology from Illumina® in combination with our global laboratory network and expert support team.
Obtain full exon coverage of 522 out of 523 genes using as little as 40 ng of DNA and 40 ng of RNA input. TSO500 can detect biomarkers without the need of a matched normal sample.
Detect multiple biomarkers with a single assay to save time, money, and samples. The distributable kit enables global implementation.
Obtain a high-resolution view of variants enabled by TSO500’s hybrid-capture chemistry and unique molecular indices (UMIs).
Gain insight into TMB score and MSI score in addition to variant calls. TruSight Oncology 500 uses an enhanced algorithm to robustly assess TMB from SNVs and indels detected in coding regions.
Our centralized, scientific operational oversight combined with our global laboratory footprint enable comprehensive, large-scale trial support. We enable clinical development support irrespective of geography.
We work with you to understand your specific needs, and our team provides cost-effective recommendations from custom assay development to specialized bioinformatics support.
Deep Sequencing Enabled by Q2 Solutions’ Subject Matter Expertise
Feel confident in your results with the trusted Illumina® software pipeline. Our software teams validate the most up-to-date software to ensure you are receiving optimal results. Q2 Solutions can develop custom reporting and filtering to meet your specific research needs. Our technical support teams help you understand your deep sequencing data with our superior bioinformatics knowledge.
Q2 Solutions provides a text-delimited, combined variant output file for all biomarkers
Validated up to CAP/CLIA standards
Q2 Solutions offers this TSO500 assay at multiple regulatory levels, from Research Use Only (RUO) to Good Clinical Practices (GCP) to CAP/CLIA, depending on the intended use of the assay by our client. Please reach out to our Q2 Solutions Genomics Business Development team to discuss your intended use so we can better guide which regulatory level is most appropriate for your clinical or research program(s).
Our centralized, scientific, and operational oversight combined with our global laboratory footprint enables comprehensive, large-scale trial support. You will be supported every step of the way by our scientific project management team who will work with you to understand the most cost-effective recommendations to meet your specific needs. We are committed to transparency so you can feel confident in our promises of quality and timely delivery. We can expert support team can meet your research needs from nearly anywhere in the world with our genomic centers in the United States, China, United Kingdom, and Singapore.
The TruSight Oncology 500 (TSO500) for tissue assay employs a hybrid capture-based approach targeting 523 genes and leverages unique molecular indices to enable detection of low allele frequency...
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