| SERVICE |
CAPABILITIES |
LOCATION AVAILABILITY |
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USA |
CHINA |
UK |
SINGAPORE |
| Anatomic pathology |
- Fresh tissue and FFPE capabilities
- H&E creation/assessment and digital slide imaging avaliable
- Pathologists onsite
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| Isolations |
- DNA and RNA extraction capabilities from a large spectrum of original material, including FFPE, blood, tissue, cells, plasma, and saliva
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| Whole human genome sequencing |
- Optimized method for FFPE and intact material, using low input and minimal amplification
- Illumina NovaSeq system available
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| DNA exome sequencing |
- Low input procedure optimized for intact and FFPE material
- Flexible hybridization method that allows for use of various standard and customized ROI probe sets
- Illumina NovaSeq system available
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| RNA sequencing |
- Globin removal method to remove globin mRNA from blood
- Library preparation from both intact and degraded RNA from FFPE, blood, tissue, and cells
- Hybridization-based method targeting the human transcriptome
- Poly-A selection method for intact material
- Ribosomal RNA depletion method for degraded and non-coding RNA
- Illumina NovaSeq system available
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| Targeted sequencing |
- Library preparations from RNA/DNA from FFPE, blood, tissues, cells, and plasma
- Hybridization-based methods targeting different panels of interest
- NovaSeq system
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| Thermo Fisher sequencing |
- Manual and Genexus library preparation with various panels
- Customizable with DNA, RNA, or simultaneous profiling available
- Genexus, Ion Chef, S5 XL and PGM Dx platforms available
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| Single cell RNA sequencing |
- Simultaneous analysis of the transcriptome and cell surface proteome
- Various assays including immune repertoire, surface protein profiling, and single-nucleus
- 10X Chromium and Illumina NovaSeq systems available
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| Spatial RNA and protein profiling |
- Customizable, spatially restricted hybridization- and antibody-based RNA and protein quantification, respectively
- Immunofluorescence-guided cell selection and stratification performed by qualified pathologists
- Targeted NanoString nCounter or whole transcriptome (i.e., 18,000+ protein-coding genes) Illumina next-generation sequencing readouts available
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| PCR assays |
- Customizable probe amplification assays for different targets of interest
- Multiple platforms for expression profiling, genotyping, and copy number analysis
- ddPCR and qPCR systems available
- Fluidigm system available at USA site
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| NanoString nCounter panels |
- Probe Hybridization based capture, RNA copies counted by nCounter
- No amplification required
- Customizable
- Up to 800 targets in a single reaction
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| Bioinformatics |
- A range of analyses to support all service lines
- Custom analysis and algorithm development including biostatistics support
- Standard pipeline analysis available globally (including China)
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Centralized in RTP |
