960 x 350_41

Next Generation Sequencing Services

Global Next Generation Sequencing (NGS) Services

With 4 global laboratory locations, Q2 Solutions offers a range of next generation sequencing services to support drug discovery, precision medicine, and clinical development. We offer expertise in assay design, development, and validation, plus a translational genomics team comprised of both assay development and bioinformatic scientists, who lead the industry in high complexity testing and analysis. Q2 Solutions offers the following next generation sequencing services:

Service Capability
Exome Sequencing
  • Low input procedure optimized for intact and FFPE material
  • Flexible hybridization method that allows for use of various standard and customized ROI probe sets
RNA Sequencing Capabilities include:
  • Library preparation from both intact and degraded RNA from FFPE, blood, tissue, and cells
Techniques include:
  • Hybridization-based method targeting the human transcriptome
  • Poly-A selection method for intact material
  • Ribosomal RNA depletion method for degraded and non-coding RNA
Whole Genome Sequencing Optimized method for FFPE and intact material, using low input and minimal amplification
DNA and RNA Isolations DNA and RNA extraction capabilities from a large spectrum of original material, including FFPE, blood, tissue, and cells
ThermoFisher in Ion Torrent AmpliSeq and Oncomine Panels
  • Library preparation and in Ion Torrent S5 XL or PGM Dx sequencing
  • DNA, RNA, or simultaneous profiling available
  • Customizable
  • Whole Transcriptome panel available
NanoString nCounter Panels
  • Probe Hybridization based capture, RNA copies counted by nCounter
  • No amplification required
  • Customizable
  • Up to 800 targets in a single reaction
Bioinformatics
  • Alignment, gene/isoform/junction counts, QC, bacterial/viral detection
  • Gene fusion detection
  • Variant calling
  • HLA allele calling
  • Group comparisons and clinical biostatistics
  • On-site support

Related Thought Leaders Insights


Robust performance of single-cell multiomic analysis (CITE-Seq) demonstrated across multiple locations, replicates, and donors on challenging cryopreserved PBMC and BMMC samples

Q2 Solutions is the first and only service provider to achieve the exclusive certified service partnership for CITE-Seq scRNA-SEQ with BioLegend. Describes CITE-seq performance expectations for...

Challenging Bioanalytical Work

If you’re looking for solutions to analytical challenges, you’ve come to the right place. Our highly trained scientists partner with you to provide a well-planned strategy, no matter where you are in...

CNS Biomarkers

Rules-Based Medicine, a Q2 Solutions company, offers ultrasensitive immunoassays – including beta-amyloids, GFAP, NF-L, and pTaus – for the development of diagnostics and therapeutics for Alzheimer’s...