960 x 350_41

In Vitro Screening

In Vitro screening plays a critical role in drug candidate optimization of ADME properties. Identifying the most promising drug candidates upfront accelerates the development cycle, reduces costs, streamlines the drug discovery pipeline, and guides subsequent pre-clinical and clinical studies. Q2 Solutions’ highly automated in vitro ADME laboratory offers a range of high-throughput ADME screening services to support the lead optimization stage of drug discovery, including assays for metabolic stability, cell permeability, and risk assessment for inhibiting cytochrome P450 enzymes.

ADME screening bundles and LC/MS bioanalytical capabilities can support your in vitro and pharmacokinetic (PK) testing

q2lab solutions images_0014_Layer 2

Early Hit-to-Lead ADME Screening Bundle

Bundled screening assays to accelerate candidate selection in drug discovery

q2lab solutions images_0001_Layer 15

High Throughput ADME Services

Capabilities that accelerate preclinical studies

Related Thought Leaders Insights

Podcast

Hybrid assays: an interview with Barry Jones and Adriane Spytko

  In this podcast Barry Jones (Director, LC–MS Biologics and Biomarkers at Q² Solutions) and Adriane Spytko (Manager, LC–MS Biologics at Q² Solutions; both NY, USA) discuss hybrid assays using both...

Infographic

Bridging the LBA and LC−MS disciplines for hybrid assays

The increasing complexity of large molecule therapeutics has driven the need for additional approaches to quantitation in regulated bioanalysis where challenges with traditional ligand binding assays...

Factsheet

Small Molecule Bioanalytical and ADME Solutions

Q2 Solutions offers tailored and comprehensive small molecule bioanalytical and ADME laboratory services. We combine scientific excellence, high-quality project management, and outstanding delivery...