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体外筛选在候选药物优化 ADME 特性中发挥关键作用。提前确定最有前景的候选药物可加速开发周期,降低成本,简化药物发现流程,指导后续的临床前和临床研究。Q2 Solutions 高自动化体外 ADME 实验室提供一系列高通量 ADME 筛选服务,以支持药物发现的先导优化阶段,包括代谢稳定性、细胞渗透性测定和抑制细胞色素 P450 酶的风险评估。

我们的 ADME 筛选组件包和 LC/MS 生物分析能力可支持您的体外和药代动力学(PK)检测

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早期先导化合物的 ADME 筛选服务包


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高通量 ADME 服务



Small Molecule Bioanalytical and ADME Solutions

Q2 Solutions offers tailored and comprehensive small molecule bioanalytical and ADME laboratory services. We combine scientific excellence, high-quality project management, and outstanding delivery...

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Analysis of a polydisperse heparin analog therapeutic (CX-01, Dociparstat) was conducted in human plasma by signature disaccharide (NS6S) analysis, with NS6S being unique to CX-01 in native human...

Hybrid assays: an interview with Barry Jones and Adriane Spytko

In this podcast Barry Jones (Director, LC–MS Biologics and Biomarkers at Q² Solutions) and Adriane Spytko (Manager, LC–MS Biologics at Q² Solutions; both NY, USA) discuss hybrid assays using both...