Genomic profiling of a tumor to characterize clinically relevant variants has become critically important for cancer diagnosis and prognosis, as well as in driving therapeutic decision making. There is a growing need for rapid assessment of somatic variants in genes of key interest in oncology. The Oncomine™ Precision Assay on the Ion Torrent™ Genexus™ Sequencer (OPAGX) is an amplicon-based automated next generation sequencing (NGS) assay that enables quick turnaround genomic profiling of RNA and DNA biomarkers across 50 genes from solid tumor and liquid biopsy samples.
The Oncomine™ Precision Assay panel contains 50 genes and 2,769 unique variants, applicable to a wide range of tumor types for detection of SNV, nsertion-Deletion, Copy Number Alterations, and Fusions. FusionSync™ technology enables detection of novel fusions.
The Genexus System is a seamless NGS solution requiring minimal user touchpoints, resulting in consistent performance and straightforward implementation to scale quickly across our global sites.
Amplicon-based library preparation utilizing unique molecular tags allows for high sensitivity while requiring minimal sample input.
Minimal input of 10ng required for FFPE and 20 ng for cfTNA*
Our centralized scientific operational oversight combined with our global laboratory footprint enables comprehensive, large-scale trial support. We enable clinical development support irrespective of geography.
*Oncomine Precision Assay detects fusions in cell-free RNA
▲ DNA Hotspots ◼ CNV ● Fusions
Image courtesy of Thermo Fisher Scientific
Our centralized scientific, and operational oversight combined with our global laboratory footprint enables comprehensive, large-scale trial support. You will be supported every step of the way by our scientific project management team who will work with you to understand the most cost-effective recommendations to meet your specific needs. We are committed to transparency so you can feel confident in our promises of quality and timely delivery. Our expert support team can meet your research needs from nearly anywhere in the world with our genomic centers in the United States, China, United Kingdom, and Singapore.
Request a quote today to discover how working with
Q2 Solutions can advance your research.
Our global central laboratory network enables testing at a single site.
Obtain in-depth data to understand gene expression, cell surface markers, immune cell repertoire, and much more.
Genomic profiling of a tumor to characterize clinically relevant variants has become critically important for cancer diagnosis and prognosis, as well as in driving therapeutic decision making. There...
Genomic profiling of a tumor to characterize clinically relevant variants has become critically important for cancer diagnosis and prognosis, as well as in driving therapeutic decision making. This...
Advances in the analysis of circulating-free DNA (cfDNA) obtained from the plasma fraction of peripheral whole blood are facilitating minimally invasive methods to monitor health and disease. As a...