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Genomics

October 17, 2022 Wendell Jones, Ph.D.

PLK3 amplification and tumor immune microenvironment of metastatic tumors are linked to adjuvant treatment outcomes in uterine serous cancer

NAR Cancer article, with contributions from Wendell Jones, PhD, Q² Solutions GenomicsUterine serous carcinoma (USC), an aggressive variant of endometrial cancer representing approximately 10% of...

Genomics

April 25, 2022 Wendell Jones, Ph.D.

Ultra-deep sequencing data from a liquid biopsy proficiency study demonstrating analytic validity

Scientific Data article, with contributions from Wendell Jones, PhD, Q² Solutions Genomics

Genomics

August 11, 2021 Wendell Jones, Ph.D.

A benchmarking study of SARS-CoV-2 whole-genome sequencing protocols using COVID-19 patient samples

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an emerging new type of coronavirus that is responsible for the COVID-19 pandemic and the unprecedented global health emergency....

Genomics

April 22, 2021 Wendell Jones, Ph.D.

Cross-oncopanel study reveals high sensitivity and accuracy with overall analytical performance depending on genomic regions

BackgroundTargeted sequencing using oncopanels requires comprehensive assessments of accuracy and detection sensitivity to ensure analytical validity. By employing reference materials characterized...

Genomics

April 22, 2021 Wendell Jones, Ph.D.

A verified genomic reference sample for assessing performance of cancer panels detecting small variants of low allele frequency

BackgroundOncopanel genomic testing, which identifies important somatic variants, is increasingly common in medical practice and especially in clinical trials. Currently, there is a paucity of...

Genomics

January 27, 2021 Patrick Hurban, Ph.D.

High-throughput toxicogenomic screening of chemicals in the environment using metabolically competent hepatic cell cultures

The ToxCast in vitro screening program has provided concentration-response bioactivity data across more than a thousand assay endpoints for thousands of chemicals found in our environment and...

Genomics

January 13, 2021 Wendell Jones, Ph.D.

Dexrazoxane enhances efficacy of all-trans retinoic acid in acute myeloid leukemia patient blast cells and cell lines

All trans retinoic acid (ATRA) has demonstrated curative activity in acute promyelocytic leukemia (APL), a distinct subtype of acute myeloid leukemia (AML), that is characterized by a chromosomal...

Genomics Central Laboratories End-to-End Services

March 3, 2020 Guy Rachmuth, Ph.D.

Implementing Strategy to Enhance Patient-Centric Care

Approach to Strategy

Genomics Central Laboratories ADME

April 23, 2018 Costa Panagos

Celebrating our medical laboratory professionals

Author: Costa PanagosDuring April 22-28, 2018, Q² Solutions is celebrating Medical Laboratory Professionals Week, also known as Lab Week. I want to take this opportunity to acknowledge and thank our...

Genomics

January 24, 2017 Victor Weigman, Ph.D.

Using Gene Signature Methodologies to strengthen Immuno Oncology Trials

The theme for this year’s World Cancer Day highlights the part we can all play in the fight against cancer. “We can. I can.” is a call to action for individuals and groups to contribute what they...

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PLK3 amplification and tumor immune microenvironment of metastatic tumors are linked to adjuvant treatment outcomes in uterine serous cancer

Ultra-deep sequencing data from a liquid biopsy proficiency study demonstrating analytic validity

A benchmarking study of SARS-CoV-2 whole-genome sequencing protocols using COVID-19 patient samples

Cross-oncopanel study reveals high sensitivity and accuracy with overall analytical performance depending on genomic regions

A verified genomic reference sample for assessing performance of cancer panels detecting small variants of low allele frequency

High-throughput toxicogenomic screening of chemicals in the environment using metabolically competent hepatic cell cultures

Dexrazoxane enhances efficacy of all-trans retinoic acid in acute myeloid leukemia patient blast cells and cell lines

Implementing Strategy to Enhance Patient-Centric Care

Celebrating our medical laboratory professionals

Using Gene Signature Methodologies to strengthen Immuno Oncology Trials