Polyclonal lymphoid expansion drives paraneoplastic autoimmunity in neuroblastoma
Cell Reports article, with contributions from Martin Buchkovich, Q2 Solutions Genomics Highlights
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PLK3 amplification and tumor immune microenvironment of metastatic tumors are linked to adjuvant treatment outcomes in uterine serous cancer
NAR Cancer article, with contributions from Wendell Jones, PhD, Q2 Solutions GenomicsUterine serous carcinoma (USC), an aggressive variant of endometrial cancer representing approximately 10% of...
Ultra-deep sequencing data from a liquid biopsy proficiency study demonstrating analytic validity
Scientific Data article, with contributions from Wendell Jones, PhD, Q2 Solutions Genomics
A benchmarking study of SARS-CoV-2 whole-genome sequencing protocols using COVID-19 patient samples
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an emerging new type of coronavirus that is responsible for the COVID-19 pandemic and the unprecedented global health emergency....
Cross-oncopanel study reveals high sensitivity and accuracy with overall analytical performance depending on genomic regions
BackgroundTargeted sequencing using oncopanels requires comprehensive assessments of accuracy and detection sensitivity to ensure analytical validity. By employing reference materials characterized...
A verified genomic reference sample for assessing performance of cancer panels detecting small variants of low allele frequency
BackgroundOncopanel genomic testing, which identifies important somatic variants, is increasingly common in medical practice and especially in clinical trials. Currently, there is a paucity of...
High-throughput toxicogenomic screening of chemicals in the environment using metabolically competent hepatic cell cultures
The ToxCast in vitro screening program has provided concentration-response bioactivity data across more than a thousand assay endpoints for thousands of chemicals found in our environment and...
Dexrazoxane enhances efficacy of all-trans retinoic acid in acute myeloid leukemia patient blast cells and cell lines
All trans retinoic acid (ATRA) has demonstrated curative activity in acute promyelocytic leukemia (APL), a distinct subtype of acute myeloid leukemia (AML), that is characterized by a chromosomal...
Celebrating our medical laboratory professionals
Author: Costa PanagosDuring April 22-28, 2018, Q2 Solutions is celebrating Medical Laboratory Professionals Week, also known as Lab Week. I want to take this opportunity to acknowledge and thank our...
