PEGS Annual Meeting


May 15, 2023 - May 19, 2023


Boston, MA USA

About This Event



Join Q2 Solutions at PEGS Boston 2023 from May 15-19 in Boston.


Monday, May 15
Challenges of Computational Antibody Design
8:20 Chairperson’s Remarks
Andrew R.M. Bradbury, PhD, CSO, Specifica, Inc


May 15-16
TS7A: Introduction to Immunogenicity

  • Sofie Pattijn, Founder & CTO, ImmunXperts, a Q2 Solutions Company
  • Chloé Ackaert, PhD, Senior Scientist, Immunogenicity, ImmunXperts, a Q2 Solutions Company

This 1.5-day training seminar provides a practical, comprehensive overview of immunogenicity – the causes, how to assess, predict and prevent, and what to do if you observe immunogenicity during preclinical, clinical and post-market approval. The seminar begins by detailing the science behind immunogenicity, the latest international Guidance, followed by assay and bioanalytical assessment strategies for traditional and emerging biologics. Other topics include predictive models and reporting immunogenicity.


Tuesday, May 16
Using Defined Human CDRs in Antibody/VHH Discovery and Optimization
Andrew Bradbury, MB BS, PhD, CSO, Specifica
The Specifica Generation-3 Library Platform is based on highly developable clinical scaffolds, into which natural CDRs purged of sequence liabilities are embedded. The platform directly yields highly diverse, high affinity, developable, drug-like antibodies, as potent as those from immune sources, with minimal need for downstream optimization. This talk will discuss extension of the Platform to VHH libraries and lead antibody improvement, with simultaneous enhancement of both affinity and developability.


Friday, May 19
Rules for Developability
8:25 Chairperson’s Remarks
M. Frank Erasmus, PhD, Head, Bioinformatics, Specifica, Inc.