TruSight Oncology 500 Comprehensive Assay​

TruSight Oncology 500 (TSO500)

Pan-cancer next-generation sequencing assay for biomarker identification and comprehensive genomic profiling across 523 genes

A Hybrid-Capture Approach for Target Enrichment of 523 Genes Across Various Tumor Types​

 

Gain an expansive view of your solid tumor samples by targeting 523 cancer-related genes using the TruSight Oncology 500 assay. Not only does this assay identify all relevant variants (SNVs, insertions, deletions, CNVs, gene fusions, and transcript variants) across various tumor types, but it also reports tumor mutational burden (TMB) and microsatellite instability (MSI) scores.​

 

Our comprehensive genomic panel has advantages over individual biomarker assays in its ability to detect multiple biomarkers with one test, saving time, money, and samples. Q2 Solutions can meet your profiling needs by leveraging trusted technology from Illumina® in combination with our global laboratory network and expert support team.

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An Efficient, Reliable Solution for Tumor Characterization

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Minimal input, extensive results

Obtain full exon coverage of 522 out of 523 genes using as little as 40 ng of DNA and 40 ng of RNA input. TSO500 can detect biomarkers without the need of a matched normal sample.

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Simple, cost-effective workflow

Detect multiple biomarkers with a single assay to save time, money, and samples. The distributable kit enables global implementation.

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Confident variant detection

Obtain a high-resolution view of variants enabled by TSO500’s hybrid-capture chemistry and unique molecular indices (UMIs).

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Measurement of key immuno-oncology biomarkers

Gain insight into TMB score and MSI score in addition to variant calls. TruSight Oncology 500 uses an enhanced algorithm to robustly assess TMB from SNVs and indels detected in coding regions.

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Expansive services enabled by our global network

Our centralized, scientific operational oversight combined with our global laboratory footprint enable comprehensive, large-scale trial support. We enable clinical development support irrespective of geography.

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Flexible customization to satisfy specific needs

We work with you to understand your specific needs, and our team provides cost-effective recommendations from custom assay development to specialized bioinformatics support.


TSO500 Variant Detection

TSO500 Variant Detection

TSO500 Assay Comparison

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Deep Sequencing Enabled by Q2 Solutions’ Subject Matter Expertise

 

Feel confident in your results with the trusted Illumina® software pipeline. Our software teams validate the most up-to-date software to ensure you are receiving optimal results. Q2 Solutions can develop custom reporting and filtering to meet your specific research needs. Our technical support teams help you understand your deep sequencing data with our superior bioinformatics knowledge.

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Deliverables

Q2 Solutions provides a text-delimited, combined variant output file for all biomarkers

  • QC Metrics
  • CNV Outputs
  • RNA Splice Variants
  • RNA Fusion Report
  • Genomic VCFs (SNVs & Indels)
  • Variant Call Annotations
  • MSI Scores
  • TMB Scores
  • FASTQs
  • BAMs

Supporting Studies Around the World

Our centralized, scientific, and operational oversight combined with our global laboratory footprint enables comprehensive, large-scale trial support. You will be supported every step of the way by our scientific project management team who will work with you to understand the most cost-effective recommendations to meet your specific needs. We are committed to transparency so you can feel confident in our promises of quality and timely delivery. We can expert support team can meet your research needs from nearly anywhere in the world with our genomic centers in the United States, China, United Kingdom, and Singapore.

 

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Learn More About TSO500 with Q2 Solutions

Simplify Your Work

 

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Request a Quote

Request a quote today to discover how TSO500 with
Q2 Solutions can advance your research.

Ship Samples​

Ship your samples to one of our global genomic laboratory centers.​

Get Results

Obtain in-depth data revealing insights into your solid tumor samples.

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