menu
Podcast
Victor Weigman, Ph.D. | August 28, 2019

The standardization of Tumor Mutational Burden (TMB) by alignments to reference standards

Joined by Friends of Cancer Research (Friends)
In this episode, we are joined by Mark Stewart from Friends of Cancer Research (Friends). Victor and Mark discuss how Tumor Mutational Burden (TMB) is different from other complex biomarkers, such as Microsatellite Instability (MSI), and the importance of standardizing these biomarkers to reference standards.

They also talk about the Friends TMB harmonization project and how this project could lead to advancements in cancer research.

To learn more about Friends of Cancer Research (Friends), visit www.focr.org.


Related Services:
The importance of TMB standardization for diagnostic assays

Standardization of TMB scores by using a common set of reference standards

TMB Standardization by Alignment to Reference Standards

Phase 2 of the Friends of Cancer Research TMB Harmonization Project

Tumor Mutational Burden (TMB) Assay for Response to Immunotherapy

TMB assay utilizing whole exome sequencing (WES) methodology and proprietary variant analysis compendium

Panel-based tumor mutational burden (TMB) analysis of matched tumor and plasma specimens using Illumina’s TruSight Oncology 500 next-generation sequencing assay

AACR 2019 Scientific Poster

Read More