Insights

Hybrid Assays for Protein Bioanalysis

Combining immuno-affinity with liquid chromatography-mass spectrometry (LC-MS)

Authors:

  • Steve Lowes, Ph.D., Senior Director, Bioanalytical Services
  • Barry Jones, Ph.D., Director, LC-MS Biologics and Biomarkers

Hybrid assays are powerful tools for protein bioanalysis of both therapeutics and endogenous biomarkers.This insight brief explains what they are, how they are used, challenges associated and their future potential.