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Q2 Solutions | EA Genomics Technology Platforms

Platforms for Biomarker Solutions

Q2 Solutions | EA Genomics leverages the below technology platforms to deliver a wide spectrum of biomarker solutions.

Service Platform Application
Next generation sequencing
  • Illumina® HiSeq 2500/4000, NovaSeq 6000 – RNA-Sequencing, Whole exome sequencing, Whole genome sequencing, miRNA sequencing
  • Illumina® MiSeq /NextSeq– Targeted gene sequencing, Viral sequencing, RNA-Sequencing, miRNA-Sequencing, 16S metagenomic sequencing
  • Thermo Fisher Ion Torrent PGM Dx and S5XL System – Targeted gene and transcript sequencing
  • ctDNA Analysis – NGS and ddPCR-based solutions
  • TCR – T Cell repertoire sequencing
  • Fluidigm® Access Arrays/Juno, Agilent SureSelect, PCR – Targeted sequencing enrichment
Sanger sequencing
  • Applied Biosystems™ SeqStudio Genetic Analyzer – Long read confirmatory sequencing
Microarray
  • Affymetrix® Genechip® Scanner 3000 – Whole Transcriptome profiling, Whole genome SNP profiling, Cytogenetic/CNV analysis, miRNA, DMET/ADME
  • Illumina® – Bead array – Whole transcriptome Profiling, Whole genome SNP profiling, Targeted SNP profiling – Mid plex
Targeted genotyping and gene expression analysis
  • Thermo Fisher QuantStudio Dx and ViiA 7 – Genotyping and gene expression (Real-Time qPCR/TaqMan)
  • Fluidigm® Dynamic Arrays – Genotyping and gene expression
  • NanoString™ nCounter® – Gene expression
  • HTG EdgeSeq – Gene expression
  • Bio-Rad QX200™ Droplet Digital™ PCR System – Genotyping and gene expression
  • NGS – Multiple enrichment technologies for Illumina® and Ion Torrent sequencing
  • ABI SeqStudio – Genotyping by Sanger sequencing
T-cell Receptor (TCR) Sequencing Assay for Characterization of Adaptive Immune Response

Detects TCRβ and TCRγ clonotypes expressed at the mRNA level

Microsatellite Instability Assay for Response to Immunotherapy

MSI assay for sensitive detection of 5 mononucleotide repeat markers in tumor FFPE specimens

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