Clinical Genomics Laboratory Services

Clinical Genomics Laboratory Services

We offer a range of genomic laboratory services to support drug discovery, precision medicine and clinical development. Our industry-leading team advances research by delivering scientific insights that help clients maximize the value of their data.

Q2 Solutions Genomics has four laboratory locations.

 

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SERVICE CAPABILITIES LOCATION AVAILABILITY
    USA CHINA UK SINGAPORE
Anatomic pathology
  • Fresh tissue and FFPE capabilities
  • H&E creation/assessment and digital slide imaging avaliable
  • Pathologists onsite
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Isolations
  • DNA and RNA extraction capabilities from a large spectrum of original material, including FFPE, blood, tissue, cells, plasma, and saliva
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Whole human genome sequencing
  • Optimized method for FFPE and intact material, using low input and minimal amplification
  • Illumina NovaSeq system available
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DNA exome sequencing
  • Low input procedure optimized for intact and FFPE material
  • Flexible hybridization method that allows for use of various standard and customized ROI probe sets
  • Illumina NovaSeq system available
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RNA sequencing
  • Globin removal method to remove globin mRNA from blood 
  • Library preparation from both intact and degraded RNA from FFPE, blood, tissue, and cells
  • Hybridization-based method targeting the human transcriptome
  • Poly-A selection method for intact material
  • Ribosomal RNA depletion method for degraded and non-coding RNA
  • Illumina NovaSeq system available
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Targeted sequencing
  • Library preparations from RNA/DNA from FFPE, blood, tissues, cells, and plasma
  • Hybridization-based methods targeting different panels of interest
  • NovaSeq system
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Thermo Fisher sequencing
  • Manual and Genexus library preparation with various panels
  • Customizable with DNA, RNA, or simultaneous profiling available
  • Genexus, Ion Chef, S5 XL and PGM Dx platforms available
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Single cell RNA sequencing
  • Simultaneous analysis of the transcriptome and cell surface proteome
  • Various assays including immune repertoire, surface protein profiling, and single-nucleus
  • 10X Chromium and Illumina NovaSeq systems available
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Spatial RNA and protein profiling
  • Customizable, spatially restricted hybridization- and antibody-based RNA and protein quantification, respectively
  • Immunofluorescence-guided cell selection and stratification performed by qualified pathologists
  • Targeted NanoString nCounter or whole transcriptome (i.e., 18,000+ protein-coding genes) Illumina next-generation sequencing readouts available
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PCR assays
  • Customizable probe amplification assays for different targets of interest
  • Multiple platforms for expression profiling, genotyping, and copy number analysis
  • ddPCR and qPCR systems available
  • Fluidigm system available at USA site
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NanoString nCounter panels
  • Probe Hybridization based capture, RNA copies counted by nCounter
  • No amplification required
  • Customizable
  • Up to 800 targets in a single reaction
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Bioinformatics
  • A range of analyses to support all service lines
  • Custom analysis and algorithm development including biostatistics support
  • Standard pipeline analysis available globally (including China)
Centralized in RTP

Regulatory standards

Our Quality Management System (QMS) is based upon the standards set forth in Good Clinical Practices (GCP), College of American Pathologists (CAP) and Clinical Laboratory Improvement Amendments (CLIA).
CAP CAP Accreditation since 2017
CLIA
(USA only)
CLIA Certified since 2010
GCP Q2 Solutions maintains a QMS that is compliant to the applicable Good Clinical Practices for clinical and genomic testing conducted
NYS
(USA only)
NYS certified since 2018
Genomics Location Map

100,000

samples isolated and 
sequenced annually

75+

assays

40+

sequencing platforms 
in operation globally

90+

bioinformaticians and 
software developers

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