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In Vitro Screening

In Vitro screening plays a critical role in drug candidate optimization of ADME properties. Identifying the most promising drug candidates upfront accelerates the development cycle, reduces costs, streamlines the drug discovery pipeline, and guides subsequent pre-clinical and clinical studies. Q2 Solutions’ highly automated in vitro ADME laboratory offers a range of high-throughput ADME screening services to support the lead optimization stage of drug discovery, including assays for metabolic stability, cell permeability, and risk assessment for inhibiting cytochrome P450 enzymes.

ADME screening bundles and LC/MS bioanalytical capabilities can support your in vitro and pharmacokinetic (PK) testing

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Early Hit-to-Lead ADME Screening Bundle

Bundled screening assays to accelerate candidate selection in drug discovery

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High Throughput ADME Services

Capabilities that accelerate preclinical studies

Related Thought Leaders Insights

Factsheet

Small Molecule Bioanalytical and ADME Solutions

Q2 Solutions offers tailored and comprehensive small molecule bioanalytical and ADME laboratory services. We combine scientific excellence, high-quality project management, and outstanding delivery...

Scientific Poster

Quantification of the Polydisperse Heparin Analog Dociparstat by Signature Disaccharide Analysis in the Presence of Concomitant Enoxaparin Dosing in Support of a Phase 2/3 Study in Patients with Severe COVID-19

Analysis of a polydisperse heparin analog therapeutic (CX-01, Dociparstat) was conducted in human plasma by signature disaccharide (NS6S) analysis, with NS6S being unique to CX-01 in native human...

Podcast

Hybrid assays: an interview with Barry Jones and Adriane Spytko

In this podcast Barry Jones (Director, LC–MS Biologics and Biomarkers at Q² Solutions) and Adriane Spytko (Manager, LC–MS Biologics at Q² Solutions; both NY, USA) discuss hybrid assays using both...