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Impact of duplicate removal on low frequency NGS somatic variant calling

Cancer genomic profiles created by analysis of targeted Next Generation Sequencing (NGS) panels is emerging as a powerful tool for making informed clinical decisions. Of the critical informatics challenges to address, accurate mutation calls and allele frequency estimations after accounting for PCR-mediated artifacts are debated.   Download our scientific poster Presented at AACR 2016 Annual Meeting and learn how to improve sensitivity of NGS panels.

Authors:
Jeran Stratfor
Gunjan Hariani
Jeff Jasper
Chad Brown
Wendell Jones, Ph.D., Principal Bioinformaticist and Scientific Advisor
Victor J. Weigman, Ph.D., Director, Translational Genomics

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