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Despite the fact that tuberculosis (TB) has been curable, it has become a global epidemic that impacts more people every year than HIV/AIDS. The millions of TB patients worldwide suffer from morbidity, mortality and Social Stigma, which can be referred to as a ‘triad of devastation.’ In recognition of World TB Day on March 24, I think it’s important to recognize just how devastating this disease has become due to the increasing spread of drug resistance, and how the clinical trial industry is working together to provide the healthcare industry and patients with a solution.   Bad news and good One of the most shocking statistics about this disease is that roughly one third of the world’s... Read More

Advances in precision medicine have led to a shift in paradigm for oncology research, from targeted therapies that rely largely on tyrosine kinase inhibitors (TKIs) to personalized therapy that can deliver demonstrable improvement in patient response along with considerably lower side effects. At the center of this trend is immunotherapy, in which researchers are developing drugs that harness the patient’s immune system to fight the cancer on its own. This research area has seen the introduction of new drugs, known as immune checkpoint inhibitors that target various pathways such as Cytotoxic T-Lymphocyte Antigen 4 (CTLA-4) or Programmed cell Death Protein 1 (PD-1). How immunotherapy... Read More

On February 4, we commemorated World Cancer Day, a day when researchers, physicians, patients and other interested groups acknowledge all the hard work being done to fight this global disease. This year in the healthcare community, we took another step closer to improving healthcare worldwide.  For years, oncology researchers dealt endless frustration over failed trials of promising drugs that inevitably worked well but only in very small groups of patients. These results were crushing, but they also led researchers to follow new paths that ultimately led them to the incredible results we are seeing today in precision medicine. By identifying the unique characteristics and genetic variants... Read More